Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/295078042?client_source=feed&format=rss
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Friday, March 29, 2013
Comedian Anderson still hurting from diving mishap
SIOUX FALLS, S.D. (AP) ? Comedian Louie Anderson says he's been in pain all week from a recent diving mishap during a taping of the ABC celebrity diving show "Splash."
Anderson, who weighs more than 400 pounds, was trying to do a flip from the 5-meter board when he slammed into the water, landing on his face and chest.
"If I were lying down right now, you would have to help me up," the 60-year-old Anderson said Wednesday. "It's been almost a week and it still hurts almost as much."
Anderson, who skipped diving practice Tuesday night to take the stage in Sioux Falls, S.D., for a show benefiting the Brennan Rock & Roll Academy, said he asked the "Splash" staff after the accident if he was suffering internal bleeding or damage but was told no.
"They said, 'That's your abs. You've never worked them,'" Anderson joked. "The last time I worked them was when I was struggling to get out of my mother. That was it, and I haven't worked them since."
The American version of "Splash," a surprise hit that originated in Europe, has Olympic gold medalist Greg Louganis coaching a diverse cast of celebrities that includes Detroit Lions lineman Ndamukong Suh, 2012 Miss Alabama Katherine Webb, basketball great Kareem Abdul-Jabbar and former Baywatch star Nicole Eggert.
Anderson said he's not alone coming away with some bumps and bruises.
"Ndamukong Suh hit his nose. Kareem Abdul-Jabbar sprained his neck," he said. "Nicole was up on a handstand and she slammed her chest and stomach into the 5-meter board and then fell into the water ? and then, two hours later, had to do the dive on TV."
Anderson, who just learned how to swim five years ago, said he decided to give the show a try after producers showed him a clip of the Netherlands version. He said it's the most exciting thing he's ever done.
"I'm at 23 feet, diving into 17 feet of water. I'm over 400 pounds," he said. "Who doesn't want to see that? I do. I'm always shocked that I can do it."
The stand-up comedian said he's glad the show is catching on with viewers.
"I didn't have any idea if it would be a hit or not," he said. "I was either going to be inspirational or a laughingstock. So I'm lucky that some people thought I did a good job."
Anderson said he's having a lot of fun, but he's also trying to win.
"I know people don't think I have a chance, but that's how I think," he said. "Why do it if you don't do it great?"
___
Follow Dirk Lammers on Twitter at http://www.twitter.com/ddlammers .
Source: http://news.yahoo.com/comedian-anderson-still-hurting-diving-mishap-015257832.html
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Meet the Lucky People Who Suddenly Owe Google $1500 (Updating)
Source: http://feeds.gawker.com/~r/gizmodo/full/~3/O5znVxKm5RY/meet-the-people-who-suddenly-owe-google-1500
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Thursday, March 28, 2013
SAfrica: Mandela responds positively to treatment
FILE - In this June 17, 2010 file photo, former South African President Nelson Mandela leaves the chapel after attending the funeral of his great-granddaughter Zenani Mandela in Johannesburg, South Africa. The South African presidency says Nelson Mandela was re-admitted to hospital with a recurrence of a lung infection Thursday March 28, 2013. (AP Photo/Siphiwe Sibeko, Pool, File)
FILE - In this June 17, 2010 file photo, former South African President Nelson Mandela leaves the chapel after attending the funeral of his great-granddaughter Zenani Mandela in Johannesburg, South Africa. The South African presidency says Nelson Mandela was re-admitted to hospital with a recurrence of a lung infection Thursday March 28, 2013. (AP Photo/Siphiwe Sibeko, Pool, File)
FILE - In this Wednesday, July 18, 2012 file photo former South African President Nelson Mandela as he celebrates his birthday with family in Qunu, South Africa, Wednesday, July 18, 2012. The South African presidency says Nelson Mandela was re-admitted to hospital with a recurrence of a lung infection Thursday March 28, 2013. (AP Photo/Schalk van Zuydam)
FILE - In this Wednesday May 30, 2012 file photo South Africa's former president Nelson Mandela, after receiving a torch to celebrate the African National Congress' centenary from ANC chairperson Baleka Mbete in Mandela's home village of Qunu in rural eastern South Africa. The South African presidency says Nelson Mandela was re-admitted to hospital with a recurrence of a lung infection Thursday March 28, 2013. (AP Photo/Lulamile Feni-Daily Dispatch) SOUTH AFRICA OUT
FILE - In this Aug. 29, 2007 file photo, former South African President Nelson Mandela pauses during a statue unveiling ceremony in his honor at Parliament Square in London. The South African presidency says Nelson Mandela was re-admitted to hospital with a recurrence of a lung infection Thursday March 28, 2013. (AP Photo/Daniel Berehulak, Pool, File)
In this photo taken on Thursday, March 14, 2013, a statue of former South African president Nelson Mandela stands at the entrance to the Robben Island ferry departure point at the V&A Waterfront in Cape Town, South Africa, Nelson Mandela, the anti-apartheid leader who became South Africa's first black president, has been admitted to a hospital with a recurring lung infection, South Africa said Thursday, March 28, 2013. Mandela, 94, has become increasingly frail in recent years and has been hospitalized several times since last year, mostly recently earlier this month when he received what a presidential spokesman described as a "successful" medical test. (AP Photo/Schalk van Zuydam)
JOHANNESBURG (AP) ? South Africa's presidency says 94-year-old Nelson Mandela is responding positively to hospital treatment for a recurring lung infection.
The office of President Jacob Zuma also said in a statement Thursday that the former president and anti-apartheid leader remains under observation.
Mandela was admitted late Wednesday to a hospital in Pretoria, the South African capital.
Mandela contracted tuberculosis during his 27-year imprisonment for fighting white racist rule in South Africa. He has repeatedly had lung problems.
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10 Things to See: A week of top AP photos
AP10ThingsToSee - A Bangladeshi Hindu child with his face smeared in colors participates in Holi festival celebrations in Dhaka, Bangladesh, Thursday, March 28, 2013. (AP Photo/A.M. Ahad, File)
AP10ThingsToSee - A Bangladeshi Hindu child with his face smeared in colors participates in Holi festival celebrations in Dhaka, Bangladesh, Thursday, March 28, 2013. (AP Photo/A.M. Ahad, File)
AP10ThingsToSee - U.S. President Barack Obama stops to look at the Treasury during his tour of the ancient city of Petra in Jordan, Saturday, March 23, 2013. (AP Photo/Pablo Martinez Monsivais, File)
AP10ThingsToSee - An aerial photo shows a landslide near Coupeville, Wash., on Whidbey Island, Wednesday, March 27, 2013. The slide severely damaged one home and isolated or threatened more than 30 on the island, about 50 miles north of Seattle in Puget Sound. No one was reported injured in the slide, which happened at about 4 a.m. Wednesday. (AP Photo/Ted S. Warren, File)
AP10ThingsToSee - A Yemeni suspected of being an al-Qaida militant listens to a judge from inside a cage during his hearing at a state security court in Sanaa, Yemen, Tuesday, March, 26, 2013. (AP Photo/Hani Mohammed, File)
AP10ThingsToSee - Egyptian protesters drag a wounded Muslim Brotherhood supporter during clashes between supporters and opponents of Egypt?s powerful Muslim Brotherhood near the Islamist group?s headquarters in Cairo, Egypt, Friday, March 22, 2013. (AP Photo/Khalil Hamra, File)
Here's your look at highlights from the weekly AP photo report, a gallery featuring a mix of front-page photography, the odd image you might have missed and lasting moments our editors think you should see.
This week's collection includes an injured Muslim Brotherhood supporter being dragged by protesters in Egypt, a massive landslide in Washington state, penitents marching in robes during Holy Week processions in Spain and a look inside a locker room during March Madness.
___
This gallery contains images published March 21, 2013 - March 28, 2013.
Follow AP photographers on Twitter: http://apne.ws/VyAhxg
___
See other recent AP photo galleries:
Cities go dark for Earth Hour: http://apne.ws/16k8gwR
Images from Holy Week around the world: http://apne.ws/XeENUN
Images from the Hindu festival of Holi: http://apne.ws/ZrhqBE
Haiti splashes slum with psychedelic colors: http://apne.ws/XeEPMh
East Coast endures another blast of winter: http://apne.ws/YIjxrC
March Madness gets into full swing: http://apne.ws/Zrhq4y
___
AP10ThingsToSee Week 1: http://apne.ws/ZWiCOl
AP10ThingsToSee Week 2: http://apne.ws/ZWiJt0
AP10ThingsToSee Week 3: http://apne.ws/10USsze
___
Follow AP Images on Twitter: https://twitter.com/AP_Images
Visit AP Images online: http://www.apimages.com
___
This gallery is curated by news producer Caleb Jones in New York: https://twitter.com/CalebNews
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Feeling down | Step Talk
Just wondering who the "oldest" SM on this site is and how did you make it as long as you have?
I have been a SM for 3 years and its so hard and not getting easier.
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There is no good age
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Outsourcing Up, But Also Hiring in U.S. - IT Business Edge
Expect a surge in outsourcing this year, according to a new study from accounting and consulting firm BDO USA.
It found 63 percent of tech companies plan to outsource or manufacture products offshore this year, up from 35 percent in 2011 ? but manufacturing makes up a big chunk of that. Still, that?s the highest rate since it began the surveys in 2008.
Its findings are based on a poll of 100 U.S. technology chief financial officers, Fox Business notes.
At the same time, 43 percent plan to boost hiring in the United States. Thirty percent said they will be hiring in research and development this year, up from 23 percent last year and 22 percent in 2011.
According to Aftab Jamil, partner and director of the technology and life sciences practice at BDO USA:
?While the drive to remain competitive has led technology companies to maintain outsourcing contracts, many are working in tandem to grow their U.S. work force to develop new and innovative products and solutions in the U.S. while outsourcing traditional 'back office' operations.?
Meanwhile, HfS Research reports that IT outsourcing, while able to cut costs and standardize processes, is failing to deliver on the goals of providing innovation and access to analytics as well as transforming organizations.
Phil Fersht, founder and CEO, writes in his Horses for Sources blog that IT outsourcing isn?t expected to get much better, though some companies are bringing some IT work back to the United States. Low-end work is outsourced, high-end work is retained. And Ferscht told me that companies might be totally happy with that -- that they don?t want to spend more on functions such as help desk and systems maintenance and may accept less-than-stellar service in those areas.
Writes Fersht:
?Ambitious CIOs these days like to focus their time on ecommerce,?mobility, ?Big Data? and?cloud strategies, and will engage IT?consultants with projects?when they need some high-end help, but most aren?t expecting their outsourcer to do that kind of work for them. ??
The only way for service providers to move up the value chain, he says, is to provide services to meet defined business goals.
?Simply put, IT provides a supporting utility to help achieve these business outcomes that clients want to buy, which would ideally be accessible in the cloud where business users can access their services wherever they want. The focus then shifts from providing widgets, to the actual provision of value, where providers start working with their clients to achieve business results, as opposed to creating simply?a low-cost environment.?
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Lawrence D. Elliott: Respectful Love
If you ever saw her on the street, the words glamour, class, and style would immediately come to mind. Her sunny smile would brighten up the most cloudy and gloomy day. Whether wearing a dark winter coat with a white silk scarf or one of her self-knitted sweaters and boots... every eye seems to focus on her the moment she enters any room or even as she walks down the most crowded street. And that includes me.
Cornelia G. Becker is not only a popular international photographer and owner of her own firm, but a published author and poet who creates emotional imagery with her words, both in her native German and in English. But there is something about her you wouldn't notice at first glance, no matter how long that "glance" is. She's also a rape survivor. This also means she's a fighter. She's fought hard to keep that smile shining and that spirit alive. And you can feel it whenever you're around her.
Lucky for me, she still believes in love. It's evident in the poems and breathtaking photographs she shares with the world. I don't know if I could have made it through such an existence in one piece. But for her, it was more than just an existence. She has chosen to live. Whenever I'm with her and see how she travels through life, it's hard to remember the bumpy and treacherous road on which she's had to navigate. Like a delicate butterfly, she lives to find the most beautiful flowers in the ugliest fields.
This, my friends, is what might be considered by the Germans as a Liebeserkl?rung -- a declaration of love. But it's more than that. This is someone for whom I have the utmost respect. Not just because of her physical beautiful, but also for the spiritual power she possesses. What is inside only enhances what is on the outside. There are those moments I discover myself transfixed as I watch her every move. I'm totally mesmerized!
But to my surprise, I find she is unaware of what a treasure she is. The fact is, not enough people have spoken of or shown to her the realities of her value. This, of course, shocks the hell out of me! It's sad how so many are all too happy to pounce on our failures, but are graveyard silent when something positive should be said.
But she carries on. And I watch. I see. I notice the attention she garners and it speaks louder than any words could. She is something special, indeed.
But I'm making up for the oversight of others. I let her know every chance I can, both in words and in deeds, just how special she truly is. I don't want her to ever forget how grateful I am to have her in my life. And it's an honor to do so because I'm a better man just being around her. My respect for her grows with each passing day. And so does my love.
?
?
?
Follow Lawrence D. Elliott on Twitter: www.twitter.com/lawrence_author
"; var coords = [-5, -72]; // display fb-bubble FloatingPrompt.embed(this, html, undefined, 'top', {fp_intersects:1, timeout_remove:2000,ignore_arrow: true, width:236, add_xy:coords, class_name: 'clear-overlay'}); });Source: http://www.huffingtonpost.com/lawrence-d-elliott/respectful-love_b_2957141.html
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PFT: Raiders to cut ties with DT Kelly
APAs the calendar approaches April, the pre-draft spin cycle will soon hit overdrive.
The rules are simple.? Teams that don?t like a player will say good things about him, hoping that someone with a higher pick will take the player, which will push a more viable prospect down the board.? Teams that like a player will say bad things about him, hoping that he?ll still be there when the team makes its pick.
It?s important to keep those rules in mind when considering any off-the-record assessments of players by scouts and coaches who, depending on the teams for which they work, may be hoping to influence what other teams will or won?t do.
Jason Cole of Yahoo! Sports spoke to scouts and coaches from multiple unnamed teams who attended the Monday Pro Day workout of Notre Dame linebacker Manti Te?o.? And none of those folks regard Te?o as a first-round pick.
?Nice player, but not worth a first-round pick.? Not in my view,? said an unnamed ?AFC personnel man.?
?He?s not a star,? an AFC head coach said.? ?If I?m taking a linebacker in the first round, I want a guy who can change my defense.? Trust me, I?ve been wrong about linebackers before, but this guy doesn?t fit the bill of what I spend a high pick on.?
?[H]e?s not good enough in my view,? an NFC defensive coordinator said.
We don?t doubt for a second that these sources said what Cole says they said.? But without knowing which team they work for, it?s impossible to know whether they really mean it.
It?s a common reality of the pre-draft process.? Scouts and coaches knock certain players, possibly because the scouts and coaches believe what they?re saying ? and possibly because they have an agenda.? When it comes to the draft, everyone has an agenda.? When it comes to the strategy-driven NFL, everyone periodically (or more often) tells untruths to advance their agenda.
We?re not saying it?s right or it?s wrong.? That?s just the way it is.? But that makes it impossible to put much stock in the things being said by unnamed sources who may be secretly hoping that the player they?re knocking slides into their laps.
Source: http://profootballtalk.nbcsports.com/2013/03/27/raiders-to-release-tommy-kelly/related/
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T-Mobile's Sonic 2.0 mobile hotspot revealed, brings LTE-powered WiFi to the masses
Filed under: Wireless, Internet, Mobile
Via: Laptop Mag
Source: T-Mobile
Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/0gRL3Jx9L6c/
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Monday, March 25, 2013
Exclusive: Hulu board contacts possible buyers of video streaming site - sources
By Ronald Grover and Jennifer Saba
LOS ANGELES/NEW YORK (Reuters) - Hulu's board has approached potential buyers to gauge their interest in buying the online video service, three sources close to the company told Reuters, as owners News Corp
The board sounded out several possible buyers as part of an internal strategic review begun recently, but it has not received a formal offer, one of the sources said on Monday, speaking on condition of anonymity because the discussions were private. It was unclear how many parties Hulu had contacted.
Hulu spokeswoman Elisa Schreiber and News Corp's Nathaniel Brown declined to comment. Disney had no immediate comment.
News Corp and Disney are also considering other options, including buying each other out, one of the sources said on Monday on condition of anonymity.
Finding a buyer will be difficult because most of Hulu's contracts with networks for programs are short term, according to Michael Pachter, an analyst with Wedbush Securities in Los Angeles who follows Hulu competitors Netflix
"Nobody will buy them unless they can fix content costs in a long-term agreement," said Pachter. "The value is based on the profit potential and without certainty about costs no rational bidder will step up."
The two media companies have for years pondered the direction of a service that now has more than 3 million subscribers to its premium service and last year generated revenue of about $700 million.
A third owner, NBC parent Comcast
The owners shopped Hulu before, rejecting bids in 2011. It also considered an initial public offering in 2010.
In October, Hulu paid hedge fund Providence Equity Partners $200 million for its 10 percent stake in the venture.
(Reporting by Ron Grover and Jennifer Saba)
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New lung cancer study takes page from Google's playbook
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Public release date: 25-Mar-2013[ | E-mail |
Share ] Contact: Robert Perkins
perkinsr@usc.edu
213-740-9226
University of Southern California
Research uses mathematical probability model to predict how lung cancer spreads
SAN DIEGO - The same sort of mathematical model used to predict which websites people are most apt to visit is now showing promise in helping map how lung cancer spreads in the human body, according to a new study published in the journal Cancer Research.
A team of researchers used an algorithm similar to the Google PageRank and to the Viterbi Algorithm for digital communication to analyze the spread patterns of lung cancer. The team includes experts from the University of Southern California (USC), Scripps Clinic, The Scripps Research Institute, University of California, San Diego Moores Cancer Center and Memorial Sloan-Kettering in New York.
"This research demonstrates how similar the Internet is to a living organism," said USC Viterbi School of Engineering Professor Paul Newton, Ph.D., the lead and corresponding author of the study. "The same types of tools that help us understand the spread of information through the web can help us understand the spread of cancer through the human body."
Employing a sophisticated system of mathematical equations known as a Markov chain model, the research team guided by USC applied mathematicians found that metastatic lung cancer does not progress in a single direction from primary tumor site to distant locations, which has been the traditional medical view. Instead, they found that cancer cell movement around the body likely occurs in more than one direction at a time.
Researchers also learned that the first site to which the cells spread plays a key role in the progression of the disease. The study showed that some parts of the body serve as "sponges" that are relatively unlikely to further spread lung cancer cells to other areas of the body. The study identified other areas as "spreaders" for lung cancer cells.
The study revealed that for lung cancer, the main spreaders are the adrenal gland and kidney, whereas the main sponges are the regional lymph nodes, liver and bone.
The study applied the advanced math model to data from human autopsy reports of 163 lung cancer patients in the New England area, from 1914 to 1943. This time period was targeted because it predates the use of radiation and chemotherapy, providing researchers a clear view of how cancer progresses if left untreated. Among the 163 patients, researchers charted the advancement patterns of 619 different metastases to 27 distinct body sites.
The study's findings could potentially impact clinical care by helping guide physicians to targeted treatment options, designed to curtail the spread of lung cancer. For example, if the cancer is found to have moved to a known spreader location, imaging tests and interventions can be quickly considered for focused treatment before the cells may be more widely dispersed. Further study is needed in this area.
Keeping tabs on cancer's movement in the body is vital to patient care. While a primary cancer tumor (confined to a single location) is often not fatal, a patient's prognosis can worsen if the cancer metastasizes that is, flakes off and travels to other parts of the body to form new tumors.
The study is part of a relatively new movement to involve physical sciences in oncology research. Mathematics probability models that interpret data from specific patient populations offer a new alternative to the established approach of relying on broader clinical trends to predict where, and how fast, cancer will spread.
###
In addition to Newton, senior contributing authors include Jeremy Mason of the USC Viterbi School of Engineering; Kelly Bethel, M.D., of Scripps Clinic; Lyudmila Bazhenova, M.D., of the UC San Diego Moores Cancer Center; Jorge Nieva, M.D., of Billings Clinic; Larry Norton, M.D., of Memorial Sloan Kettering Cancer Center; and Peter Kuhn, Ph.D., of The Scripps Research Institute.
The study was conducted at the Scripps Physics Oncology Center (http://4db.us) and was funded by a grant U54CA143906 to Kuhn from the National Cancer Institute and the Gates Millennium Fellowship Program of the Bill and Melinda Gates Foundation.
Scripps Health provides comprehensive care at its five hospital campuses and its various outpatient facilities. With more than 300 affiliated physicians, Scripps Cancer Care seeks to provide the best possible treatment and cutting-edge research trials for patients by coordinating medical expertise in the areas of clinical cancer care, community outreach and clinical, translational and basic research.
ABOUT SCRIPPS HEALTH
Founded in 1924 by philanthropist Ellen Browning Scripps, Scripps Health is a $2.6 billion nonprofit integrated health system based in San Diego, Calif. Scripps Health treats a half-million patients annually through the dedication of 2,600 affiliated physicians and 13,500 employees among its five acute-care hospital campuses, home health care services, and an ambulatory care network of physician offices and 24 outpatient centers and clinics.
Recognized as a leader in the prevention, diagnosis, and treatment of disease, Scripps Health is also at the forefront of clinical research, genomic medicine, wireless health care and graduate medical education. With three highly respected graduate medical education programs, Scripps Health is a longstanding member of the Association of American Medical Colleges and is recognized by Truven Health Analytics (formerly Thomson Reuters) for having one of the top teaching hospitals in the nation. Scripps Health is also the region's only cardiovascular program recognized by U.S. News & World Report as one of the best in the country. Scripps Health has been consistently recognized by Fortune, Working Mother magazine and AARP as one of the best places in the nation to work. More information can be found at http://www.scripps.org.
ABOUT THE SCRIPPS RESEARCH INSTITUTE
The Scripps Research Institute (TSRI) is one of the world's largest independent, not-for-profit organizations focusing on research in the biomedical sciences. Over the past decades, TSRI has developed a lengthy track record of major contributions to science and health, including laying the foundation for new treatments for cancer, rheumatoid arthritis, hemophilia, and other diseases. The institute employs about 3,000 people on its campuses in La Jolla, CA, and Jupiter, FL, where its renowned scientistsincluding three Nobel laureateswork toward their next discoveries. The institute's graduate program, which awards PhD degrees in biology and chemistry, ranks among the top ten of its kind in the nation. For more information, see http://www.scripps.edu.
ABOUT THE USC VITERBI SCHOOL OF ENGINEERING
Engineering Studies began at the University of Southern California in 1905. Nearly a century later, the Viterbi School of Engineering received a naming gift in 2004 from alumnus Andrew J. Viterbi, inventor of the Viterbi algorithm now key to cell phone technology and numerous data applications. Consistently ranked among the top graduate programs in the world, the school enrolls more than 5,000 undergraduate and graduate students, taught by 177 tenured and tenure-track faculty, with 60 endowed chairs and professorships. http://viterbi.usc.edu
ABOUT UC SAN DIEGO MOORES CANCER CENTER
UC San Diego Moores Cancer Center is home to nearly 350 medical and radiation oncologists, cancer surgeons, and researchers. It is one of only 41 National Cancer Institute-designated comprehensive cancer centers in the country, a rare honor distinguishing exceptionally high achievement in research, clinical care, education and community outreach and partnerships. For more information, visit http://www.cancer.ucsd.edu.
Contact: Steve Carpowich
858-678-7183
carpowich.stephen@scrippshealth.org
Contact: Mika Ono
858-784-2052
mikaono@scripps.edu
Contact: Scott LaFee
619-543-6163
slafee@ucsd.edu
Contact: Megan Hazle
213-821-1555
hazle@usc.edu
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Public release date: 25-Mar-2013[ | E-mail |
Share ] Contact: Robert Perkins
perkinsr@usc.edu
213-740-9226
University of Southern California
Research uses mathematical probability model to predict how lung cancer spreads
SAN DIEGO - The same sort of mathematical model used to predict which websites people are most apt to visit is now showing promise in helping map how lung cancer spreads in the human body, according to a new study published in the journal Cancer Research.
A team of researchers used an algorithm similar to the Google PageRank and to the Viterbi Algorithm for digital communication to analyze the spread patterns of lung cancer. The team includes experts from the University of Southern California (USC), Scripps Clinic, The Scripps Research Institute, University of California, San Diego Moores Cancer Center and Memorial Sloan-Kettering in New York.
"This research demonstrates how similar the Internet is to a living organism," said USC Viterbi School of Engineering Professor Paul Newton, Ph.D., the lead and corresponding author of the study. "The same types of tools that help us understand the spread of information through the web can help us understand the spread of cancer through the human body."
Employing a sophisticated system of mathematical equations known as a Markov chain model, the research team guided by USC applied mathematicians found that metastatic lung cancer does not progress in a single direction from primary tumor site to distant locations, which has been the traditional medical view. Instead, they found that cancer cell movement around the body likely occurs in more than one direction at a time.
Researchers also learned that the first site to which the cells spread plays a key role in the progression of the disease. The study showed that some parts of the body serve as "sponges" that are relatively unlikely to further spread lung cancer cells to other areas of the body. The study identified other areas as "spreaders" for lung cancer cells.
The study revealed that for lung cancer, the main spreaders are the adrenal gland and kidney, whereas the main sponges are the regional lymph nodes, liver and bone.
The study applied the advanced math model to data from human autopsy reports of 163 lung cancer patients in the New England area, from 1914 to 1943. This time period was targeted because it predates the use of radiation and chemotherapy, providing researchers a clear view of how cancer progresses if left untreated. Among the 163 patients, researchers charted the advancement patterns of 619 different metastases to 27 distinct body sites.
The study's findings could potentially impact clinical care by helping guide physicians to targeted treatment options, designed to curtail the spread of lung cancer. For example, if the cancer is found to have moved to a known spreader location, imaging tests and interventions can be quickly considered for focused treatment before the cells may be more widely dispersed. Further study is needed in this area.
Keeping tabs on cancer's movement in the body is vital to patient care. While a primary cancer tumor (confined to a single location) is often not fatal, a patient's prognosis can worsen if the cancer metastasizes that is, flakes off and travels to other parts of the body to form new tumors.
The study is part of a relatively new movement to involve physical sciences in oncology research. Mathematics probability models that interpret data from specific patient populations offer a new alternative to the established approach of relying on broader clinical trends to predict where, and how fast, cancer will spread.
###
In addition to Newton, senior contributing authors include Jeremy Mason of the USC Viterbi School of Engineering; Kelly Bethel, M.D., of Scripps Clinic; Lyudmila Bazhenova, M.D., of the UC San Diego Moores Cancer Center; Jorge Nieva, M.D., of Billings Clinic; Larry Norton, M.D., of Memorial Sloan Kettering Cancer Center; and Peter Kuhn, Ph.D., of The Scripps Research Institute.
The study was conducted at the Scripps Physics Oncology Center (http://4db.us) and was funded by a grant U54CA143906 to Kuhn from the National Cancer Institute and the Gates Millennium Fellowship Program of the Bill and Melinda Gates Foundation.
Scripps Health provides comprehensive care at its five hospital campuses and its various outpatient facilities. With more than 300 affiliated physicians, Scripps Cancer Care seeks to provide the best possible treatment and cutting-edge research trials for patients by coordinating medical expertise in the areas of clinical cancer care, community outreach and clinical, translational and basic research.
ABOUT SCRIPPS HEALTH
Founded in 1924 by philanthropist Ellen Browning Scripps, Scripps Health is a $2.6 billion nonprofit integrated health system based in San Diego, Calif. Scripps Health treats a half-million patients annually through the dedication of 2,600 affiliated physicians and 13,500 employees among its five acute-care hospital campuses, home health care services, and an ambulatory care network of physician offices and 24 outpatient centers and clinics.
Recognized as a leader in the prevention, diagnosis, and treatment of disease, Scripps Health is also at the forefront of clinical research, genomic medicine, wireless health care and graduate medical education. With three highly respected graduate medical education programs, Scripps Health is a longstanding member of the Association of American Medical Colleges and is recognized by Truven Health Analytics (formerly Thomson Reuters) for having one of the top teaching hospitals in the nation. Scripps Health is also the region's only cardiovascular program recognized by U.S. News & World Report as one of the best in the country. Scripps Health has been consistently recognized by Fortune, Working Mother magazine and AARP as one of the best places in the nation to work. More information can be found at http://www.scripps.org.
ABOUT THE SCRIPPS RESEARCH INSTITUTE
The Scripps Research Institute (TSRI) is one of the world's largest independent, not-for-profit organizations focusing on research in the biomedical sciences. Over the past decades, TSRI has developed a lengthy track record of major contributions to science and health, including laying the foundation for new treatments for cancer, rheumatoid arthritis, hemophilia, and other diseases. The institute employs about 3,000 people on its campuses in La Jolla, CA, and Jupiter, FL, where its renowned scientistsincluding three Nobel laureateswork toward their next discoveries. The institute's graduate program, which awards PhD degrees in biology and chemistry, ranks among the top ten of its kind in the nation. For more information, see http://www.scripps.edu.
ABOUT THE USC VITERBI SCHOOL OF ENGINEERING
Engineering Studies began at the University of Southern California in 1905. Nearly a century later, the Viterbi School of Engineering received a naming gift in 2004 from alumnus Andrew J. Viterbi, inventor of the Viterbi algorithm now key to cell phone technology and numerous data applications. Consistently ranked among the top graduate programs in the world, the school enrolls more than 5,000 undergraduate and graduate students, taught by 177 tenured and tenure-track faculty, with 60 endowed chairs and professorships. http://viterbi.usc.edu
ABOUT UC SAN DIEGO MOORES CANCER CENTER
UC San Diego Moores Cancer Center is home to nearly 350 medical and radiation oncologists, cancer surgeons, and researchers. It is one of only 41 National Cancer Institute-designated comprehensive cancer centers in the country, a rare honor distinguishing exceptionally high achievement in research, clinical care, education and community outreach and partnerships. For more information, visit http://www.cancer.ucsd.edu.
Contact: Steve Carpowich
858-678-7183
carpowich.stephen@scrippshealth.org
Contact: Mika Ono
858-784-2052
mikaono@scripps.edu
Contact: Scott LaFee
619-543-6163
slafee@ucsd.edu
Contact: Megan Hazle
213-821-1555
hazle@usc.edu
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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Source: http://www.eurekalert.org/pub_releases/2013-03/uosc-nlc032213.php
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Chiropractor in Kent WA Can Help Your Migraines
Chiropractor in Kent WA will assist in providing relief for your migraines. Migraine headaches are painful and can also be debilitating at times, preventing the sufferer from accomplishing anything worthy of note. People who experience this pain report that they just want to lie down somewhere, turn off the lights, and close all the curtains as even the tiniest stimulus can cause the painful throbbing to worsen. If you are suffering from migraines, there is help available to you today. Chiropractor in Kent WA does not use invasive surgeries or dangerous medications. Their alternative chiropractic therapy such as massage therapy and spinal decompression therapy is designed to naturally and successfully treat the root causes of migraines, leaving you healthier and stronger.
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UFC Quick Quote: Rafael dos Anjos wants to be first Brazilian lightweight champion
Ahead of his UFC on FX 8 meeting with Evan Dunham this May, UFC lightweight Rafael dos Anjos lets it be known that his ultimate goal in the sport is to become the first-even Brazilian lightweight champion in the world's premier MMA organization.
"Always every fight I want to show up, I want to put on a good show for all people, and my goal is to get that belt because never has any Brazilian got that belt in the lightweight division, so I want to be the first one."
-- Ultimate Fighting Championship (UFC) lightweight contender Rafael dos Anjos tells Aaron Tru that he is planning on becoming the first-ever Brazilian champion at 155-pounds in the history of the UFC. Dos Anjos is currently the No. 8 ranked lightweight in the official UFC rankings and is riding a three-fight UFC win-streak. Next up for the 28-year-old is a UFC on FX 8 match up with Evan Dunham, a fight that could help elevate Dos Anjos very near to title contention. While Brazilian fighters dominate most of the weight classes in mixed martial arts (MMA) and currently three fighters from the country hold UFC belts; only one Brazilian has ever competed for the lightweight title, and that man was Hermes Franca, who came up short in his title fight against Sean Sherk way back at UFC 73 in July 2007.
Do you think dos Anjos has a chance of becoming the first-ever Brazilian lightweight champion in the UFC? Let us know in the comments section below.
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How will climate change affect the Himalayas? Scientists trek to find out.
Almost half of the world gets its water from the Himalayas and other high mountains, but little is known about how global warming will affect these sources. A team of scientists ventured to the roof of the world to investigate.?
Rinchen Zoe plateau, Bhutan Himalaya.
David Putnam
EnlargeThe distribution of water in Asia's highest mountains and driest deserts tells an important story of climate change.
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Almost half the world's population gets its water from glacier melt and rainfall in the Himalayas and other lofty peaks, yet little is understood about how climate change will affect these water sources. Now, using sophisticated technology and old-fashioned fieldwork, scientists are looking into the past to solve this mystery.
"We're trying to understand the relationships between climate and glaciers and Earth's water resources from the perspective of Earth's paleoclimate," geologist Aaron Putnam of the Lamont Doherty Earth Observatory said in a talk at the Columbic Club in New York on March 12. He described his recent expeditions along the Silk Road, from the Tien Shan Mountains to the Taklamakan Desert to the Bhutanese Himalayas.
Tien Shan Mountains
Putnam and colleagues set out in 2010 to the Tarim Basin in Northwest China, right in the center of Asia. Within the Tien Shan Mountains, a range that extends some 1,740 miles (2,800 kilometers), the scientists studied masses of soil and rock debris built up by glaciers, called moraines, which held clues to the past climate. [Stunning Scenes: From the Himalayas to the Taklamakan Desert]
To determine the ages of the moraines, the researchers used a technique known as beryllium-10 exposure dating. Cosmic radiation constantly bombards the Earth's surface, changing the form of some of the elements, like beryllium, in rocks. Based on these changes, the scientists could determine how long the moraines had been there, which allowed researchers to reconstruct the glaciers' past positions. "We can see what the ice looked like and know exactly when the ice was there," Putnam said.
Deep in the desert
Next, Putnam and colleagues ventured to the Taklamakan Desert. New roads have made the desert accessible, "so we were able to access lands people had died trying to visit even a decade ago," Putnam said. He described the area as a parched, desolate landscape with endless expanses of sand dunes.
As the researchers trekked through the desert, they noticed silts, mud cracks, remnants of trees, even shells ? all telltale signs of water. To find out when this wet period took place, the scientists used radiocarbon dating, a technique that measures the ratio of different forms of carbon to find an object's age. The scientists also used dendrochronology, a method of determining trees' ages based on their growth rings. The results suggested the wet period occurred from the mid-1100s to the late 1800s.
Putnam and his team then traveled to the easternmost part of the desert to an enormous dry lakebed called Lop Nor. They did radiocarbon dating of shells on the lake's shoreline, finding the shells' ages matched those of the other samples from formerly wet areas. That span of time, from the 12th century to the 19th century, was a cold period in North Atlantic regions. "When it got cold in the North Atlantic, it got wet in the mid-latitude desert regions," Putnam said.
The onset of wet conditions in the Taklamakan Desert corresponds with the rise of Genghis Khan and the Mongol Empire, the largest contiguous land empire in history. The Mongols relied heavily on horses, which would have needed lots of grass to eat. Putnam and his team think the wetting of the desert allowed grasslands to expand, enabling the Mongols to spread throughout Asia. [10 Surprising Ways Weather Changed History]
Atop the Himalayas
Next, Putnam and his colleagues headed south to the Himalayas of Bhutan, an area swept by the monsoon. "We don't know how the monsoon will affect glacier behavior in the Himalayas," Putnam said, adding, "We just needed to go there and use good old-fashioned fieldwork to figure it out." The team made a six-day trek to their study site, a glacier-laden plateau.
The journey wasn't easy; it took 25 horses and mules to carry all of the supplies from the deep jungles up to the icy peaks. The team hiked over 15,400-foot-high (4,700 meters) mountain passes, home to creatures like the Himalayan blue sheep, or bharal.
Finally, the team crested Bhutan's Rinchen Zoe plateau. They ventured out onto the glaciers and took ice sample to measure the amount of melt. The scientists used the same beryllium dating method as before to determine the age of the glacial deposits, work that is currently in progress. The team had to leave before the snows came with the approaching winter.
Though the scientists haven't finished their analysis yet, it's clear that the glaciers have substantially receded over the last century, Putnam said, and this will have an impact on the many people who depend on the mountains for water.
With the current global warming trend, Putnam expects to see a northward expansion of the deserts. The insights gained on these expeditions were only possible through fieldwork, Putnam said. "In my opinion, there's no substitute for collecting fundamental data from the natural world," he said.
Follow Tanya Lewis @tanyalewis314. Follow us @livescience, Facebook?or Google+. Original article on LiveScience.com.
Copyright 2013 LiveScience, a TechMediaNetwork company. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.
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What goes on in Japan Starbucks and Subway?
goo Ranking seems to have started an interesting series looking at what typical behaviour one has experienced in food chains, with the first two being looked at being Starbucks and Subway.
Demographics
Over the 6th and 7th of March 2013 over 1,000 members of the goo Research monitor group completed a private internet-based questionnaire. However, the link to the full demographics is not operating right now? Note that the score in the results refers to the relative number of votes for each option, not a percentage of the total sample.
I actually prefer Tully?s to Starbucks ? Tully?s is usually not quite so packed, and their menu actually looks like a coffee shop menu. There?s probably also an element of me not wanting to be seen in place with so many foreigners?
I haven?t been to Subway for a while, although I will agree with number 15, their fried potato is excellent.
Ranking result
Read more on: goo ranking,starbucks,subwayQ1: What typical behaviour have you experienced in Starbucks? (Sample size=over 1,000)
Rank ? Score 1 Feeling healed by the smell of coffee throughout the shop 100 2 Lots of people studying, so nowhere to sit 90.2 3 Not knowing much about the kinds of coffee, so choosing based on the impression of the product names 85.8 4 When ordering with a lid to carry out, drinking through the small hole and burning the tip of my tongue 79.1 5 Feeling happy when staff offer me a sample of cake 47.1 6 Good taste in background music, giving the place a feeling of elegance 44.3 7 When hungry, ordering too many side dishes then later feeling regret when I realise the price I paid 43.4 8 Sitting in a too comfy sofa and spending too long there 41.5 9 As city centre shops are usually packed, feeling downhearted when I cannot sit 40.0 10 Feeling admiration for foreigners looking cool while drinking on the pavement seats 37.2 11 Feeling angry when someone who ordered after me gets their drink made first 33.2 12 When the cup is hot, not knowing the word ?Sleeve? and instead gesturing and asking for ?That thingie please? 27.4 13 Disregarding the high calories, ordering from the side menu 25.8 14 Feeling a frisson of excitement when the staff draw a cute picture on my paper cup 24.0 15= Feeling envious of the high percentage of Mac-using customers 23.4 15= When the staff calls out the order ?Tall coco!?, etc, I repeat the refrain in my heart 23.4 17 Being joyous when the staff gently catch my attention as I hum and haw over what to order 21.5 18 Overdoing it on the condiment bar and masking out the original taste 20.6 19 Since a refill of drip coffee is 100 yen, overdosing on coffee 18.8 20 Lots of cool/cute staff make my heart beat faster 17.2 21 Since there are more foreigner customers than other chains, heart beats a little faster 13.5 22 Having a violent end to a fight over a mains socket 12.6 23 Getting into poverty from visiting Starbucks too often 12.0 24 Buying the new tumblers every season, and ending up with my home overflowing with tumblers 11.1 25 Forgetting to return the ?Soy milk? card when they pass me my drink 5.5 Q2: What typical behaviour have you experienced in Subway? (Sample size=over 1,000)
Rank ? Score 1 Being nervous about not knowing how to order 100 2 My eyes get drawn to the seasonal menu 83.6 3 Always getting my bread toasted 63.6 4 Tending to order the ?Special Sub? 55.2 5 When I have an empty stomach, tending to order a large chicken-related sub 44.8 6 Ending up saying ?All veggies are fine? 44.2 7 Ending up usually adding avocado topping 37.6 8 Usually carrying a discount coupon from their web site with me 30.9 9 Tending to order as much extra tomato as I can 28.5 10 Getting them to remove the veggies I don?t like ends up with a plain old sandwich 26.7 11 Feeling joy from the bottom of my heart when the egg sandwich reappears on the menu 26.1 12= Wishing that they would serve their winter soups all year round 23.6 12= Tending to get addicted to having sliced cheese toasted with the bread 23.6 14 Seeing a dream of me ordering a Giant Sub one day 23.0 15 Ending up thinking Subway make the tastiest fried potato 21.8 16= Ending up trying all six dressings on a single sub 16.4 16= Tending to always order a cookie from the side menu 16.4 18 Ordering without bread when dieting and ending up with just a salad 12.1 19 Ending up ordering a wrap 9.7 20 Secretly desiring to try out the Subway Diet 8.5
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EA apologizes for 'SimCity' launch woes
In this image provided by Electronic Arts/Maxis, a concept art image of an accident scene in an urban area is shown as concept art for the video game "SimCity." The creators of ?SimCity? are hoping players don't move on after connectivity issues plagued the game's launch last week. The updated edition of the 24-year-old metropolis-building franchise released last Tuesday, March 5, 2013, requires players to be online _ even if they're constructing virtual cities in the single-player mode. Several gamers weren't able to log on after ?SimCity? launched, prompting some retailers to stop selling the Electronic Arts Inc. game. (AP Photo/Electronic Arts/Maxis)
In this image provided by Electronic Arts/Maxis, a concept art image of an accident scene in an urban area is shown as concept art for the video game "SimCity." The creators of ?SimCity? are hoping players don't move on after connectivity issues plagued the game's launch last week. The updated edition of the 24-year-old metropolis-building franchise released last Tuesday, March 5, 2013, requires players to be online _ even if they're constructing virtual cities in the single-player mode. Several gamers weren't able to log on after ?SimCity? launched, prompting some retailers to stop selling the Electronic Arts Inc. game. (AP Photo/Electronic Arts/Maxis)
FILE - In this file image provided by Electronic Arts/Maxis, concept art for a waterfront city is shown for the video game "SimCity." The creators of ?SimCity? are hoping players don't move on after connectivity issues plagued the game's launch last week. The updated edition of the 24-year-old metropolis-building franchise released last Tuesday, March 5, 2013, requires players to be online _ even if they're constructing virtual cities in the single-player mode. Several gamers weren't able to log on after ?SimCity? launched, prompting some retailers to stop selling the Electronic Arts Inc. game. (AP Photo/Electronic Arts/Maxis, File)
LOS ANGELES (AP) ? The creators of "SimCity" are hoping players don't move on after connectivity issues plagued the game's launch last week.
The updated edition of the 24-year-old metropolis-building franchise released last Tuesday requires players to be online ? even if they're constructing virtual cities in the single-player mode. Several gamers weren't able to log on after "SimCity" launched, prompting some retailers to stop selling the Electronic Arts Inc. game.
Lucy Bradshaw, general manager at "SimCity" developer Maxis, said Friday more wannabe mayors logged on than they anticipated and that the developers have been increasing server capacity since the snafu.
"More people played and played in ways we never saw in the beta," said Bradshaw. "OK, we agree, that was dumb, but we are committed to fixing it. In the last 48 hours, we increased server capacity by 120 percent. It's working ? the number of people who have gotten in and built cities has improved dramatically."
Bradshaw said EA would give players a free PC game to compensate for the hassles. Players who registered copies of "SimCity" will receive details on how to download the free game March 18.
"I know that's a little contrived ? kind of like buying a present for a friend after you did something crummy," she said. "But we feel bad about what happened. We're hoping you won't stay mad and that we'll be friends again when 'SimCity' is running at 100 percent."
___
Online:
http://www.simcity.com/
___
Follow AP Entertainment Writer Derrik J. Lang on Twitter at http://www.twitter.com/derrikjlang
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